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Table 2 Genes that act as a genomic classifier for response to treatment of psoriasis with Alefacept.

From: Personalized medicine in psoriasis: developing a genomic classifier to predict histological response to Alefacept

Probe

Symbol

Description

Gene

av-rank-in- CV

prop- selected-in-CV

32067_at

CREM

cAMP responsive element modulator

1390

2.71

1.00

36711_at

MAFF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)

23764

2.86

1.00

36131_at

CLIC1

chloride intracellular channel 1

1192

4.71

1.00

40296_at

SASH3

SAM and SH3 domain containing 3

54440

11.71

0.86

36909_at

WEE1

WEE1 homolog (S. pombe)

7465

11.29

0.86

41122_at

AOF2

amine oxidase (flavin containing) domain 2

23028

14.86

1.00

32317_s_at

SULT1A3

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3

6818

14.14

0.71

1309_at

PSMB3

proteasome (prosome, macropain) subunit, beta type, 3

5691

15.14

0.57

35980_at

PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

23236

18.71

0.71

31804_f_at

SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

6817

17.29

0.71

37127_at

NLRP1

NLR family, pyrin domain containing 1

22861

16.86

0.86

37029_at

ATP5O

ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)

539

18.86

0.57

37417_at

POU2F2

POU class 2 homeobox 2

5452

20.86

0.71

35083_at

FTL

ferritin, light polypeptide

2512

20.86

0.57

1404_r_at

CCL5

chemokine (C-C motif) ligand 5

6352

25.43

0.57

34279_at

NBPF10

neuroblastoma breakpoint family, member 10

440673

35.14

0.43

38791_at

DDOST

dolichyl-diphosphooligosaccharide-protein glycosyltransferase

1650

24

0.57

35823_at

PPIB

peptidylprolyl isomerase B (cyclophilin B)

5479

23.71

0.86

41344_s_at

PURA

purine-rich element binding protein A

5813

26.29

0.71

464_s_at

IFI35

interferon-induced protein 35

3430

34

0.57

39867_at

TUFM

Tu translation elongation factor, mitochondrial

7284

27.43

0.43

1676_s_at

EEF1G

eukaryotic translation elongation factor 1 gamma

1937

27.71

0.71

35821_at

HDAC3

histone deacetylase 3

8841

29.57

0.43