Cost-effectiveness of oral alitretinoin in patients with severe chronic hand eczema - a long-term analysis from a Swiss perspective

Table 1 Resource utilisation

Cost item	Costs per month (€)	Dosage per month	Ref.
Basis costs for alitretinoin group
Alitretinoin 30 mg capsules	28 × €17.50 = € 490	28 × 30 mg (one capsule per day)	[19]
Emollients	€ 25	200gr	Official price in Swiss pharmacies
Pregnancy testing + oral contraceptives	€ 19	1 test, 21 tab	[19]
Dermatologist visits	€ 27	1 visit	[20]
Lipid monitoring tests^#	€ 11	1 test	[44]
Basis costs for placebo group
Emollients	€ 25	200gr	Official price in Swiss pharmacies
Dermatologist visits	€ 27	1 visit	[20]
Following costs for non-responders (alitretinoin or supportive care): Conventional local therapy for severe non-responders
Emollients	€ 25	200gr	Official price in Swiss pharmacies
Dermatologist visits	€ 27	1 visit	[20]
PUVA/311 nm (Topical/oral)	€ 121	20 cycles per 10 weeks in 6 months period (3,33 cycles per month)	[20]
Topical steroids Class I-III	€ 30	60 gr	[19]
Topical steroids Class IV	€ 17	60 gr	[19]
Topical steroids total*	€ 20	60 gr	[19]

^#LDL, HDL, Triglycerides.
*Assumes 25% of the patients treated with Class I-III and 75% with Class IV topical steroids

ISSN: 1471-5945