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Table 1 Crude associations between risk factors at baseline and the incidence of asthma and rhinitis*

From: Eczema in early childhood is strongly associated with the development of asthma and rhinitis in a prospective cohort

Risk factor at baseline

Total number in category n (%)

Number with asthma n

Asthma OR (95% CI)

P-value

Number with rhinitis n

Rhinitis OR (95% CI)

P-value

Eczema

   

<0.001

  

<0.001

No

2,573 (82.4)

101

1.0

 

107

1.0

 

Yes

551 (17.6)

49

2.85 (1.72-4.71)

 

65

3.14 (2.27-4.36)

 

Persistence of eczema

      

<0.001

No

2,886 (92.4)

58

1.0

<0.001

135

1.0

 

Yes

238 (7.6)

15

4.20 (2.31-7.64)

 

37

3.92 (2.64-5.82)

 

Onset of eczema

      

<0.001

No

2,483 (80.6)

46

1.0

<0.001

98

1.0

 

Age ≥ one year

216 (6.9)

6

1.87 (0.7-4.45)

 

8

0.96 (0.46-2.00)

 

Age < one year

386 (12.6)

21

3.63 (2.12-6.22)

 

66

5.02 (3.58-7.05)

 

Eczema severity

      

<0.001

No

2,478 (79.47)

45

1.0

<0.001

98

1.0

 

Mild

468 (15.0)

17

2.42 (1.36-4.29)

 

47

2.74 (1.90-3.95)

 

Moderate to severe

173 (5.5)

11

4.55 (2.27-9.12)

 

27

4.74 (2.98-7.55)

 

Gender

      

0.001

Female

1,546 (49.5)

25

1.0

0.002

65

1.0

 

Male

1,579 (50.5)

48

2.16 (1.32-3.54)

 

107

1.67 (1.21-2.29)

 

Age of the child

      

0.727

12-23 month

1,557 (49.8)

41

1.0

0.325

88

1.0

 

24-35 month

1,568 (50.2)

32

0.79 (0.49-1.27)

 

84

0.95 (0.70-1.29)

 

Parental history of allergic disease

      

<0.001

No parent

1,594 (51.0)

26

1.0

<0.001

47

1.0

 

One parent

1,199 (38.4)

32

1.92 (1.14-3.25)

 

83

2.45 (1.69-3.53)

 

Two parents

332 (10.6)

15 (7.2)

3.67 (1.90-7.08)

 

42

4.85 (3.12-7.55)

 

Asthma in the child

      

<0.001

No

2,843 (91.4)

--

--

 

147

1.0

 

Yes

269 (8.6)

--

--

--

25

4.10 (2.57-6.54)

 

Length of breastfeeding

      

0.791

Longer than 6 month

2,043 (65.9)

44

1.0

0.021

112

1.0

 

Up to 6 months

974 (31.4)

23

1.14 (0.68-1.90)

 

54

1.02 (0.73-1.43)

 

No breastfeeding

82 (2.7)

6

3.32 (1.36-8.11)

 

6

1.35 (0.57-3.16)

 

Number of bedrooms with PVC

      

0.116

No PVC in bedroom

1,300 (42.8)

23

1.0

0.184

60

1.0

 

PVC in one bedroom

558 (18.4)

14

1.42 (0.72-2.79)

 

38

1.51 (0.99-2.30)

 

PVC in two bedrooms

1,183 (38.9)

34

1.65 (0.96-2.82)

 

70

1.31 (0.92-1.87)

 

Type of building

      

0.453

Single-family house

2,522 (82.4)

58

1.0

0.902

137

1.0

 

Multi-family house

538 (17.6)

12

1.04 (0.55-1.96)

 

33

1.13 (0.75-1.70)

 

Parental smoking

      

0.357

No

2,431 (77.8)

56

1.0

0.691

139

1.0

 

Yes

694 (22.2)

17

1.12 (0.64-1.94)

 

33

0.83 (0.56-1.23)

 

Number of adults living with the child

      

0.830

Two or more adults

2,853 (93.8)

66

1.0

0.320

157

1.0

 

One adult

190 (6.2)

6

1.54 (0.65-3.62)

 

11

1.07 (0.57-2.01)

 
  1. 3,124 children aged 1–2 in 2000 in Värmland, Sweden, were included in the analysis.
  2. *during the 5-year follow-up period.