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Table 1 Changes in MASI scores of tested drugs in melasma patients

From: The treatment of melasma by silymarin cream

  

MASI

Treatment

Baseline

After 1stweek

After 2nd week

After 3rd week

After 4th week

G I: SM 7 mg/ml

17.1 ± 3.12

12.3 ± 2.3a

6.6 ± 2.4b

0.2 ± 1.72b

0b

G II: SM 14 mg/ml

16.5 ± 2.8

10.4 ± 1.2a

3.5 ± 1.4b

0b

0b

G III: Placebo

16.8 ± 3.2

16.8 ± 3.3c

16.8 ± 3.5c

17 ± 3.4c

17 ± 3.4c

  1. a p ≤ 0.01, b p ≤ 0.0001, c p ≥ 0.05.