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Table 3 Sensitivity analysis: excluding children who had recently seen a specialist

From: Improved emollient use reduces atopic eczema symptoms and is cost neutral in infants: before-and-after evaluation of a multifaceted educational support programme

 

Pre-Programme1

 

Programme2

 

Change3,4

   
 

Mean

(SD)

Mean

(SD)

Mean

95% CI4

N

p4

Emollient Use (g/wk)

        

 Daily diary

69.7

(49.5)

170.3

(99.0)

100.6

(81.9 to 119.5)

114

0.001

 Time to use

72.2

(49.6)

184.3

(97.6)

112.2

(94.6 to 131.3)

99

0.001

Severity Scores

 POEM

11.03

(6.49)

5.83

(4.67)

-5.20

(-6.39 to -4.34)

117

0.001

 PEST

2.26

(0.82)

1.66

(0.62)

-0.60

(-0.74 to -0.47)

117

0.001

Cost (£, 2011)

 Programme

  

32.00

-

32.00

-

-

-

 Emollient [A]

8.18

(5.80)

19.98

(11.61)

11.81

(9.81 to 14.01)

114

0.001

 Emollient [B]

8.47

(5.82)

21.63

(11.46)

13.16

(10.94 to 15.39)

99

0.001

 GP visits

63.23

(63.80)

30.46

(30.86)

-32.77

(-45.77 to -19.77)

117

0.001

 Overall cost [A]

71.81

(66.37)

83.25

(33.75)

11.44

(-1.99 to 24.86)

114

0.123

 Overall cost [B]

72.11

(68.24)

83.45

(33.75)

11.35

(-3.14 to 25.83)

99

0.239

  1. 1 Estimated for the 12 weeks preceding intervention, using 2 week baseline data and 12 week recall (GP visits).
  2. 2 Twelve weeks while receiving the patient support programme.
  3. 3 Difference in costs in the two periods (negative denotes a reduction).
  4. 4 Estimated by bootstrapping with 1,000 replications.
  5. A Emollient use costed using the daily diary method.
  6. B Emollient use costed using the estimated time taken to use a 500 g pot of emollient.