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Table 3 Sensitivity analysis: excluding children who had recently seen a specialist

From: Improved emollient use reduces atopic eczema symptoms and is cost neutral in infants: before-and-after evaluation of a multifaceted educational support programme

  Pre-Programme1   Programme2   Change3,4    
  Mean (SD) Mean (SD) Mean 95% CI4 N p4
Emollient Use (g/wk)         
 Daily diary 69.7 (49.5) 170.3 (99.0) 100.6 (81.9 to 119.5) 114 0.001
 Time to use 72.2 (49.6) 184.3 (97.6) 112.2 (94.6 to 131.3) 99 0.001
Severity Scores
 POEM 11.03 (6.49) 5.83 (4.67) -5.20 (-6.39 to -4.34) 117 0.001
 PEST 2.26 (0.82) 1.66 (0.62) -0.60 (-0.74 to -0.47) 117 0.001
Cost (£, 2011)
 Programme    32.00 - 32.00 - - -
 Emollient [A] 8.18 (5.80) 19.98 (11.61) 11.81 (9.81 to 14.01) 114 0.001
 Emollient [B] 8.47 (5.82) 21.63 (11.46) 13.16 (10.94 to 15.39) 99 0.001
 GP visits 63.23 (63.80) 30.46 (30.86) -32.77 (-45.77 to -19.77) 117 0.001
 Overall cost [A] 71.81 (66.37) 83.25 (33.75) 11.44 (-1.99 to 24.86) 114 0.123
 Overall cost [B] 72.11 (68.24) 83.45 (33.75) 11.35 (-3.14 to 25.83) 99 0.239
  1. 1 Estimated for the 12 weeks preceding intervention, using 2 week baseline data and 12 week recall (GP visits).
  2. 2 Twelve weeks while receiving the patient support programme.
  3. 3 Difference in costs in the two periods (negative denotes a reduction).
  4. 4 Estimated by bootstrapping with 1,000 replications.
  5. A Emollient use costed using the daily diary method.
  6. B Emollient use costed using the estimated time taken to use a 500 g pot of emollient.