Haplotype | Frequency in AD patients (n = 470) | Frequency in controls (n = 320) | p-value |
---|---|---|---|
Block 1 | |||
1112122 | 0.619 | 0.511 | 2.9x10 -5 |
2221211 | 0.134 | 0.182 | 0.0114 |
2221212 | 0.086 | 0.088 | 0.8954 |
2222222 | 0.060 | 0.070 | 0.4447 |
1212122 | 0.023 | 0.019 | 0.607 |
1122222 | 0.022 | 0.016 | 0.4152 |
2221222 | 0.016 | 0.021 | 0.4906 |
2112122 | 0.012 | 0.025 | 0.0465 |
Block 2 | |||
12121 | 0.718 | 0.650 | 0.0043 |
12112 | 0.113 | 0.110 | 0.8506 |
12212 | 0.074 | 0.106 | 0.0305 |
21122 | 0.079 | 0.093 | 0.3379 |
12122 | 0.007 | 0.022 | 0.0083 |