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Table 2 Frequencies and p-values of LAMA3 haplotypes in AD patients and controls

From: Association of variation in the LAMA3 gene, encoding the alpha-chain of laminin 5, with atopic dermatitis in a German case–control cohort

Haplotype

Frequency in AD patients (n = 470)

Frequency in controls (n = 320)

p-value

Block 1

   

1112122

0.619

0.511

2.9x10 -5

2221211

0.134

0.182

0.0114

2221212

0.086

0.088

0.8954

2222222

0.060

0.070

0.4447

1212122

0.023

0.019

0.607

1122222

0.022

0.016

0.4152

2221222

0.016

0.021

0.4906

2112122

0.012

0.025

0.0465

Block 2

   

12121

0.718

0.650

0.0043

12112

0.113

0.110

0.8506

12212

0.074

0.106

0.0305

21122

0.079

0.093

0.3379

12122

0.007

0.022

0.0083

  1. Bold: significant results.