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Table 2 Univariate analysis of exposures and risk of eczema since birth

From: Risk factors for eczema in infants born in Cuba: a population-based cross-sectional study

Variable

Definition of category

Number (%) unless stated otherwise

Prevalence of eczema (%)

OR for eczema using survey command (95% CI)

Mother used paracetamol in pregnancy (%)

No

1809 (92)

626 (35)

1

Yes

147 (8)

46 (31)

0.86 (0.43-1.73)

Mother used aspirin in pregnancy (%)

Never

1778 (91)

596 (34)

1

Yes

178 (9)

76 (43)

1.48 (0.72-3.05)

Infant’s mean birth weight, kg, (sd)

 

3.34 (0.53)

n/a

0.98 (0.84-1.13) per kg

Infant’s mean height at birth cm (sd)*

 

50.28 (2.38)

n/a

1.02 (0.99-1.06) per cm

Infant’s mean weight, kg, (sd)

 

10.52 (1.56)

n/a

1.14 (1.04-1.26) per kg

Infant’s mean height, cm (sd)

 

74.67 (3.72)

n/a

1.02 (1.00-1.03) per cm

Caesarean birth (%)

No

1163 (59)

394 (34)

1

Yes

793 (41)

278 (35)

1.05 (0.73-1.52)

Respiratory distress at birth (%)

No

1836 (94%)

620 (34)

1

Yes

120 (6%)

52 (43)

1.50 (1.04-2.16)

Breastfeeding ≥4 months

No

890 (45)

337 (38)

1

Yes

1066 (55)

335 (31)

0.75 (0.56-1.01)

Family history of asthma

No

917 (47)

267 (29)

1

Yes

1039 (53)

405 (39)

1.56 (1.32-1.83)

Insect sting allergy (%)

No

933 (48)

229 (25)

1

Yes

1022 (52)

443 (43)

2.35 (1.56-3.56)

Missing

1

  

Paracetamol use by infant including kogrip (%)

No

1486 (76)

486 (33)

1

Yes

470 (24)

186 (40)

1.35 (1.12-1.62)

Antibiotic use by infant

No

1255 (64)

363 (29)

1

Yes

696 (36)

307 (44)

1.94 (1.40, 2.68)

State of home (%)

Good

1368 (70)

477 (35)

1

Regular

463 (24)

149 (32)

0.87 (0.77-1.01)

Poor

125 (6)

46 (37)

1.09 (0.40-2.98) p = 0.13 p(trend) = 0.84

No. of rooms in house (excluding bathroom and kitchen)

1

246 (13)

91 (37)

1

2

540 (28)

167 (31)

0.76 (0.38-1.54)

≥3

1170 (60)

414 (35)

0.93 (0.44-1.99) p = 0.35 p(trend) = 0.83

Ventilation of home (%)

Good

1535 (78)

524 (34)

1

Regular

307 (16)

102 (33)

0.96 (0.72-1.28)

Poor

114 (6)

46 (40)

1.31 (0.70-2.44) p = 0.62 p(trend) = 0.31

Presence of ornamental plants (%)

No

1405 (72)

484 (34)

1

Yes

551 (28)

188 (34)

0.99 (0.77-1.26)

Presence of bathroom in home (%)

No

255 (13)

96 (38)

1

Yes

1701 (87)

576 (34)

0.85 (0.59-1.22)

Mould in home (%)

No

1385 (71)

443 (32)

1

Yes

571 (29)

229 (40)

1.42 (1.19-1.70)

Child sleeps in cooking area

No

1774 (91)

592 (33)

1

Yes

182 (9)

80 (44)

1.57 (1.17-2.10)

Cook with gas (%)

No

133 (7)

64 (48)

1

Yes

1823 (93)

608 (33)

0.54 (0.32-0.90)

Cook with electricity (%)

No

1507 (77)

482 (32)

1

Yes

449 (23)

190 (449)

1.56 (0.99-2.45)

Mosquito nets in home (%)

No

728 (37)

240 (33)

1

Yes

1228 (63)

432 (35)

1.10 (0.83-1.47)

Air conditioning (%)

No

1619 (83)

565 (35)

1

Yes

337 (17)

107 (32)

0.87 (0.72-1.05)

Infant’s room walls painted before birth

No

953 (49)

321 (34)

1

Yes

1003 (51)

351 (35)

1.06 (0.85-1.32)

Infant’s room walls painted after birth

No

1713 (88)

580 (34)

1

Yes

243 (12)

92 (38)

1.19 (0.66-2.16)

Infant’s mattress

Used

1062 (54)

374 (35)

1

New

894 (46)

298 (33)

0.92 (0.67-1.26)

Infant sleeps alone

No (not alone)

829 (42)

297 (36)

1

Yes (alone)

1127 (58)

375 (33)

0.89 (0.62-1.30)

Daily use of soap

No

69 (4)

26 (38)

1

Yes

1887 (96)

646 (34)

0.86 (0.33-2.22)

Use of shampoo

No

615 (31)

209 (34)

1

Yes

1341 (69)

463 (35)

1.02 (0.69-1.52)

No. of people in household

2

237 (12)

75 (32)

1

3

485 (25)

170 (35)

1.17 (0.54-2.49)

4

551 (28)

178 (32)

1.03 (0.50-2.14)

5

332 (17)

116 (35)

1.16 (0.74-1.83)

≥6

351 (18)

133 (38)

1.32 (0.63-2.74) P = 0.80 p(trend) = 0.20

Eats vegetables

No

350 (18)

115 (33)

1

Yes

1606 (82)

557 (35)

1.08 (0.75-1.57)

Eats fruit

No

184 (9)

65 (35)

1

Yes

1772 (91)

607 (34)

0.95 (0.49-1.85)

Maternal smoking during pregnancy

No

1779 (91)

609 (34)

1

Yes

177 (9)

63 (36)

1.06 (0.67-1.67)

Mother currently smokes

No

1557 (80)

513 (33)

1

Yes

399 (20)

159 (40)

1.35 (0.92-1.97)

Father currently smokes

No

1309 (67)

434 (33)

1

Yes

647 (33)

238 (37)

1.17 (0.83-1.65)

Number of smokers in home

0

952 (49)

299 (31)

1

1

494 (25)

176 (36)

1.21 (0.90-1.62)

2

340 (17)

131 (39)

1.37 (0.86-2.17)

≥3

170 (9)

66 (39)

1.39 (0.89-2.15) P = 0.31 p(trend) = 0.03

Any grandparents smoke

No

832 (43)

274 (33)

1

Yes

1124 (57)

398 (35)

1.12 (0.83-1.50)

Pets in home at time of birth

No

1259 (64)

417 (33)

1

Yes

697 (36)

255 (37)

1.16 (0.70-1.93)

Pets in home now

No

1239 (63)

419 (34)

1

Yes

717 (37)

253 (35)

1.07 (0.74-1.52)

Rodents in home

No

1643 (84)

534 (32)

1

Yes

313 (16)

138 (44)

1.64 (1.33-2.02)

Cockroaches in home

No

1432 (73)

470 (33)

1

Yes

524 (27)

202 (39)

1.28 (0.77-2.14)

Air pollution near home

No

1407 (72)

476 (34)

1

Yes

549 (28)

196 (36)

1.09 (0.57-2.08)

Child attended daycare/nursery

No

1685 (86)

559 (33)

1

Yes

271 (14)

113 (42)

1.44 (1.14-1.83)

Any parasites**

No

686 (96)

262 (38)

1

Yes

26 (4)

9 (35)

0.86 (0.23-3.21)

Any wheeze

No

1084 (55)

280 (26)

1

Yes

872 (45)

392 (45)

2.34 (1.56-3.53)

  1. *5 missing values.
  2. **1244 infants were unable to provide a faeces sample for analysis.