HLA class II alleles may influence susceptibility to adult dermatomyositis and polymyositis in a Han Chinese population

Table 3 Comparisons of frequencies of HLA class II putative haplotypes between DM and PM and controls

Haplotypes	DM (N =63)	PM (N = 18)	Myositis with ILD	Myositis with dysphagia	Control (N =100)	Controls vs. indicated patients ( p; OR [95% CI])
*DRB1-DQA1-DQB1*	n (%)	n (%)	n (%) N = 36	n (%), N = 9	n (%)	DM	PM	Myositis with ILD	Myositis with dysphagia
03-05-02	2 (1.59)	2 (5.56)	2 (2.78)	0 (0.00)	11 (5.50)	n/s	n/s	n/s	n/s
04-03-03	6 (4.36)	1 (2.78)	5 (6.94)	1 (5.56)	9 (4.50)	n/s	n/s	n/s	n/s
04-03-04	5 (3.97)	2 (5.56)	5 (6.94)	1 (5.56)	6 (3.00)	n/s	n/s	n/s	n/s
07-01-02	12 (9.52)	1 (2.78)	8 (11.11)	2 (11.11)	7 (3.50)	0.03¹; 2.90	n/s	0.02¹; 3.45	n/s
07-01-02	12 (9.52)	1 (2.78)	8 (11.11)	2 (11.11)	7 (3.50)	(1.02–8.93)	n/s	(1.04–11.58)	n/s
07-03-02	6 (4.76)	0 (0.00)	3 (4.17)	2 (11.11)	11 (5.50)	n/s	n/s	n/s	n/s
08-01-06	13 (10.32)	3 (8.33)	6 (8.33)	2 (11.11)	13 (6.50)	n/s	n/s	n/s	n/s
09-03-03	17 (13.49)	2 (5.56)	3 (4.17)	3 (16.67)	20 (10.00)	n/s	n/s	n/s	n/s
11-05-03	3 (2.38)	1 (2.78)	1 (1.39)	0 (0.00)	7 (3.50)	n/s	n/s	n/s	n/s
12-01-03	11 (8.73)	2 (5.56)	8 (11.11)	0 (0.00)	11 (5.50)	n/s	n/s	n/s	n/s
13-01-06	7 (5.56)	0 (0.00)	2 (2.78)	1 (5.56)	7 (3.50)	n/s	n/s	n/s	n/s
14-01-05	2 (1.59)	1 (2.78)	0 (0.00)	2 (11.11)	7 (3.50)	n/s	n/s	n/s	n/s
15-01-06	7 (5.56)	3 (8.33)	3 (4.17)	1 (5.56)	19 (9.50)	n/s	n/s	n/s	n/s

n/s: not significant; n/a: not applicable; ¹ p corr greater than 0.05; ILD: interstitial lung disease.

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