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Figure 1 | BMC Dermatology

Figure 1

From: Calcium and Vitamin D increase mRNA levels for the growth control hIK1 channel in human epidermal keratinocytes but functional channels are not observed

Figure 1

hIK1 mRNA expression is upregulated in human epidermal keratinocytes under culture conditions which are anti-proliferative/pro-differentiating. Keratinocytes were grown in either proliferative (0.06 mM calcium), or anti-proliferative, pro-differentiating culture conditions (2 mM calcium, 1 μM VitD, or both) for 1, 3, and 5 days. Total mRNA was harvested and processed for real-time PCR analysis. hIK1 mRNA levels are expressed as % of GAPDH mRNA, with data values at the top of each respective column. Each column represents the mean ± SEM for 2 to 6 cultures treated as indicated. The far right data column is broken to allow scaling of the y-axis appropriate to the lower expression values. * indicates significant difference from 0.06 mM calcium treatment at the indicated number of days.

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BMC Dermatology

ISSN: 1471-5945

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