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Table 5 Estimated doses of cyanotoxins by the cutaneous route

From: Cutaneous hypersensitivity reactions to freshwater cyanobacteria – human volunteer studies

Cyanotoxin

Dose per subject

Dose by weight*

Mouse LD50(i.p.)

Cylindrospermopsin

160 ng

2.4 ng/kg

2.1 mg/kg (24 hours); 200 μg/kg (5–6 days) [31]

Microcystins

170 ng

2.6 ng/kg

45–70 μg/kg (most toxic forms) [32 (p. 140)]

Saxitoxins

3.8 ng

58 pg/kg

10–30 μg/kg [32 (p. 140)]

  1. *Dose by weight estimated for a 65 kg individual