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Table 2 Retrospective SPC results (Good control level) at week 12

From: Evaluation of efalizumab using safe psoriasis control

Study

Treatment Group

Safe Psoriasis Control (SPC)*

ACD2058[14]

Placebo (n = 170)

18 (10.6 %)

 

Efalizumab 1.0 mg/kg/wk (n = 162)

75 (46.3 %)

ACD2059[13]

Placebo (n = 122)

12 (9.8 %)

 

Efalizumab 1.0 mg/kg/wk (n = 232)

86 (37.1 %)

ACD2390[12]

Placebo (n = 187)

20 (10.7 %)

 

Efalizumab 1.0 mg/kg/wk (n = 369)

140 (37.9 %)

Pooled studies

Placebo (n = 479)

50 (10.4%)

 

Efalizumab 1.0 mg/kg/wk (n = 763)

301 (39.4%)

  1. * SPC is defined by PASI <= 8 and DLQI <= 6 and No SAEs and No Severe AEs related to Study Drug and not withdrawn