Table 3 Distribution of EGF genotypes and allele frequencies in Italy among melanoma and non-melanoma subjects.
Genotype | Healthy controls (%) | Melanoma patients (%) | Odds ratio* (95% CI) |
|---|---|---|---|
North Italy | Â | Â | Â |
A/A | 45 (35.7%) | 51 (28.3%) | 1.00 |
A/G | 58 (46.0%) | 91 (50.6%) | 1.26 (0.58–2.43) |
G/G | 23 (18.3%) | 38 (21.1%) | 1.39 (0.38–2.77) |
Total cases | 126 | 180 | Â |
Allele | Â | Â | Â |
A | 148 (59%) | 193 (54%) | 1.00 |
G | 104 (41%) | 167 (46%) | 1.28 (0.63–2.14) |
South Italy | Â | Â | Â |
A/A | 48 (37.2%) | 93 (39.1%) | 1.00 |
A/G | 59 (45.7%) | 115 (48.3%) | 1.02 (0.36–1.98) |
G/G | 22 (17.1%) | 30 (12.6%) | 0.63 (0.22–1.46) |
Total cases | 129 | 238 | Â |
Allele | Â | Â | Â |
A | 155 (60%) | 301 (63%) | 1.00 |
G | 103 (40%) | 175 (37%) | 0.84 (0.31–1.55) |