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Table 3 Distribution of EGF genotypes and allele frequencies in Italy among melanoma and non-melanoma subjects.

From: Role of the EGF +61A>G polymorphism in melanoma pathogenesis: an experience on a large series of Italian cases and controls

Genotype Healthy controls (%) Melanoma patients (%) Odds ratio* (95% CI)
North Italy    
A/A 45
(35.7%)
51
(28.3%)
1.00
A/G 58
(46.0%)
91
(50.6%)
1.26
(0.58–2.43)
G/G 23
(18.3%)
38
(21.1%)
1.39
(0.38–2.77)
Total cases 126 180  
Allele    
A 148
(59%)
193
(54%)
1.00
G 104
(41%)
167
(46%)
1.28
(0.63–2.14)
South Italy    
A/A 48
(37.2%)
93
(39.1%)
1.00
A/G 59
(45.7%)
115
(48.3%)
1.02
(0.36–1.98)
G/G 22
(17.1%)
30
(12.6%)
0.63
(0.22–1.46)
Total cases 129 238  
Allele    
A 155
(60%)
301
(63%)
1.00
G 103
(40%)
175
(37%)
0.84
(0.31–1.55)
  1. *adjusted for age and sex. CI, confidence interval