Description of familial keloids in five pedigrees: evidence for autosomal dominant inheritance and phenotypic heterogeneity

Table 1 Characteristics of five families with familial keloids

Family	Ethnicity	Generations studied	Subjects	Affected subjects (keloids)	Unaffected subjects (with hypertrophic scars)	Unaffected Subjects (no abnormal scars)	Unknown status
F	African American	4	15	9	2	3	1
K	African American	3	12	8	0	4	0
R	African American	3	4	3	1	0	0
D	Afro-Caribbean	2	18	5	0	13	0
H	East Indian	5	24	11	1	11	1
Total		17	73	36	4	31	2

The characteristics of the five families with familial keloids are shown, including 70 family members overall. Two patients in the study could not be contacted to determine presence or absence of keloids. Children <18 yrs are excluded from this table as keloids often appear during adolescence.

ISSN: 1471-5945