Skip to main content

Table 5 Summary of improvements in HRQoL measures in response to etanercept by treatment group

From: Effect of etanercept therapy on psoriasis symptoms in patients from Latin America, Central Europe, and Asia: a subset analysis of the PRISTINE trial

Adjusted mean change from baseline

Week 12

Week 24

QW/QW n = 86

BIW/QW n = 84

QW/QW n = 86

BIW/QW n = 84

DLQI, mean (SEM)

−8.4 (0.5)

−10.8 (0.5)

−9.5 (0.6)

−11.0 (0.6)

EQ-5D, mean (SEM)

0.2 (0.0)

0.3* (0.0)

0.2* (0.0)

0.3* (0.0)

WPAI: % activity impairment due to problem, mean (SEM)

−19.1 (2.3)

−25.1 (2.3)

−22.1 (2.2)

−27.3 (2.3)

WPAI: % impairment while working due to problem, mean (SEM)

−7.5 (2.5)

−16.3 (2.6)*

−11.8 (2.0)

−18.8 (2.0)*

WPAI: % overall work impairment due to problem, mean (SEM)

−7.8 (3.3)

−15.1 (3.2)

−13.5 (2.8)

−16.3 (2.8)

WPAI: % work time missed due to problem, mean (SEM)

−3.4 (2.6)

0.4 (2.5)

−6.1 (2.3)

0.6 (2.3)*

Total FACIT, mean (SEM)

3.2 (0.7)

4.5 (0.7)

4.5 (0.8)

4.3 (0.8)

  1. Missing data were imputed using the last observation carried forward method
  2. *p < 0.05 between treatment groups at the same time point. p < 0.01 from baseline within treatment group
  3. BIW twice weekly, DLQI Dermatology Life Quality Index, EQ-5D EuroQoL 5 Dimension, FACIT Functional Activity in Chronic Therapy, HRQoL health-related quality of life, QW once weekly, SEM standard error of the mean, WPAI Work Productivity and Activity Impairment scale