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Fig. 4 | BMC Dermatology

Fig. 4

From: The first Danish family reported with an AQP5 mutation presenting diffuse non-epidermolytic palmoplantar keratoderma of Bothnian type, hyperhidrosis and frequent Corynebacterium infections: a case report

Fig. 4

Aquagenic wrinkling, also known as “hand-in-the-bucket-sign” revealed by water immersion test. Upper panel: Palmar phenotype after water immersion test of only the right hand. After three minutes in water, the palmar skin on the right hand was clearly affected by translucent white papules and a whitish spongy appearance, compared to the left side which had not been exposed to water. Lower panel: Spongy appearance on affected skin due to swelling of the stratum corneum after three minutes exposure to water

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BMC Dermatology

ISSN: 1471-5945

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