Table 3 Changes in treatment group from starting treatment for patients treated with monotherapy or combination therapy
Starting treatment groupa | New treatment group | Percentage switched n (%) | Median (days)b | IQR |
|---|---|---|---|---|
Topical, n = 44,603 | Phototherapy | 1613 (3.6) | 48.0 | 0.0–296.0 |
Oral Systemic | 2232 (5.0) | 139.0 | 14.0–327.3 | |
Biologic | 2841 (6.4) | 135.0 | 15.0–283.0 | |
Oral Systemic + Biologic | 9 (0.0) | 30.0 | 0.0–48.0 | |
Multiple Switch | 11,927 (26.7) | 79.0 | 7.0–243.0 | |
No Switch | 25,981 (58.2) | 327.0 | 174.8–365.0 | |
Phototherapy, n = 5248 | Topical | 2438 (46.5) | 84.0 | 33.0–185.0 |
Oral Systemic | 19 (0.4) | 113.0 | 53.0–149.0 | |
Biologic | 18 (0.3) | 79.0 | 44.3–142.5 | |
Oral Systemic + Phototherapy | 45 (0.9) | 56.0 | 5.0–239.0 | |
Biologic + Phototherapy | 17 (0.3) | 76.0 | 21.0–189.0 | |
Other Interventions | 665 (12.7) | 35.0 | 3.0–97.0 | |
Multiple Switch | 726 (13.8) | 98.0 | 45.0–182.0 | |
No Switch | 1320 (25.2) | 160.0 | 55.0–350.7 | |
Oral Systemic, n = 7116 | Topical | 1751 (24.6) | 105.0 | 21.0–219.0 |
Oral Systemic | 7 (0.1) | 0.0 | 0.0–111.0 | |
Biologic | 6 (0.1) | 34.5 | 7.0–134.8 | |
Oral Systemic + Phototherapy | 19 (0.3) | 2.0 | 0.0–166.5 | |
Oral Systemic + Biologic | 73 (1.0) | 35.0 | 0.0–100.0 | |
Other Interventions | 445 (6.3) | 33.0 | 0.0–136.0 | |
Multiple Switch | 2459 (34.6) | 117.0 | 45.0–215.5 | |
No Switch | 2356 (33.1) | 159.0 | 61.0–299.1 | |
Biologic, n = 11,767 | Topical | 1857 (15.8) | 191.0 | 83.0–290.2 |
Oral Systemic | 5 (0.0) | 317.0 | 0.0–342.2 | |
Biologic | 5 (0.0) | 42.0 | 39.0–87.0 | |
Biologic + Phototherapy | 15 (0.1) | 7.0 | 0.0–204.9 | |
Oral Systemic + Biologic | 80 (0.7) | 204.8 | 39.5–302.5 | |
Other Interventions | 800 (6.8) | 0.0 | 0.0–186.6 | |
Multiple Switch | 4669 (39.7) | 112.0 | 15.0–227.0 | |
No Switch | 4336 (36.9) | 238.0 | 139.0–319.8 | |
Oral Systemic + Phototherapy, n = 146 | Topical | 10 (6.9) | 52.5 | 36.5–141.5 |
Phototherapy | 10 (6.9) | 165.0 | 146.8–240.6 | |
Oral Systemic | 14 (9.6) | 88.5 | 31.0–132.8 | |
Multiple Switch | 99 (67.8) | 90.0 | 40.5–156.0 | |
No Switch | 13 (8.9) | 54.0 | 20.0–144.0 | |
Biologic + Phototherapy, n = 65 | Biologic | 9 (12.0) | 91.0 | 28.0–227.0 |
Multiple Switch | 56 (74.7) | 70.0 | 38.8–148.0 | |
Oral Systemic + Biologic, n = 350 | Oral Systemic | 18 (5.1) | 81.5 | 3.8–210.5 |
Biologic | 54 (15.2) | 144.5 | 49.8–227.0 | |
Multiple Switch | 237 (66.8) | 94.0 | 35.0–189.0 | |
No Switch | 41 (11.6) | 140.1 | 48.0–298.5 | |
Oral Systemic + Biologic + Phototherapy, n = 5 | Multiple Switch | 5 (100.0) | 137.0 | 109.0–196.0 |
Other Interventions, n = 13,200 | Topical | 1782 (13.5) | 25.5 | 0.0–140.0 |
Phototherapy | 408 (3.1) | 0.0 | 0.0–0.0 | |
Oral Systemic | 491 (3.7) | 0.0 | 0.0–86.0 | |
Biologic | 1488 (11.3) | 12.0 | 0.0–158.3 | |
Multiple Switch | 4835 (36.6) | 13.0 | 0.0–102.5 | |
No Switch | 4196 (31.8) | 265.0 | 115.9–365.0 |