Table 1 Signaling pathways under control of differently expressed microRNAs in melanoma, healthy adjacent skin, and normal skin
From: Differences in microRNA expression between melanoma and healthy adjacent skin
1 № | 2 KEGG pathway/Pathway ID | 3 P-value | 4 #Genes | 5 #miRNAs |
|---|---|---|---|---|
1. | Fatty acid metabolism (hsa 01212) | 1.9665081572e-20 | 16 | 2 |
2. | Fatty acid biosynthesis (hsa 00061) | 3.88343729046e-12 | 4 | 1 |
3. | Fatty acid degradation (hsa 00071) | 1.1705763613e-07 | 13 | 2 |
4. | Viral carcinogenesis (hsa 05203) | 8.9531652961e-07 | 58 | 3 |
5. | Cell cycle (hsa04110) | 1.46761453192e-05 | 44 | 3 |
6. | Thyroid hormone signaling pathway (hsa 04919) | 0.00023866494053 | 34 | 3 |
7. | Lysine degradation (hsa 00310) | 0.000277746132555 | 18 | 2 |
8. | Fatty acid elongation (hsa 00062) | 0.000393862316908 | 5 | 2 |
9. | Adherens junction (hsa 04520) | 0.000600606807405 | 24 | 3 |
10. | Protein processing in endoplasmic reticulum (hsa 04141) | 0.000719067931089 | 52 | 4 |
11. | Hepatitis B (hsa 05161) | 0.000831189493265 | 41 | 4 |
12. | Colorectal cancer (hsa 05210) | 0.00105284269565 | 21 | 4 |
13. | Chronic myeloid leukemia (hsa 05220) | 0.0011487759517 | 26 | 2 |
14. | Glioma (hsa 05214) | 0.00117316207454 | 22 | 2 |
15. | Valine, leucine and isoleucine degradation (hsa 00280) | 0.0014848528083 | 15 | 2 |
16. | Proteoglycans in cancer (hsa 05205) | 0.0014848528083 | 53 | 4 |
17. | p53 signaling pathway (hsa 04115) | 0.00271217599064 | 25 | 3 |
18. | Progesterone-mediated oocyte maturation (hsa 04914) | 0.00299144080019 | 30 | 4 |
19. | Pancreatic cancer (hsa 05212) | 0.00339287122318 | 23 | 2 |
20. | Endocytosis (hsa 04144) | 0.00740160464535 | 55 | 4 |
21. | Valine, leucine and isoleucine biosynthesis (hsa 00290) | 0.00936978210372 | 2 | 2 |
22. | Oocyte meiosis (hsa 04114) | 0.00936978210372 | 31 | 3 |
23. | Sphingolipid metabolism (hsa 00600) | 0.0158257005999 | 13 | 2 |
24. | Melanoma (hsa 05218) | 0.0231238970517 | 20 | 2 |
25. | TNF signaling pathway (hsa 04668) | 0.0273433465936 | 30 | 3 |
26. | Bladder cancer (hsa 05219) | 0.035250285817 | 15 | 2 |
27. | FoxO signaling pathway (hsa 04068) | 0.0377717190064 | 38 | 4 |
28. | Endometrial cancer (hsa 05213) | 0.0377780248664 | 16 | 3 |