Table 5 Comparisons of mean differences in ADCT total score by PGAD and DLQI known groups

 Baseline

Excellent

3

8.67 (7.64)

–

–

–

–

Very good

31

9.90 (5.88)

Excellent vs very good

−1.24 (−8.64, 6.16)

0.736

−0.17^a

Good

240

12.85 (5.44)

Very good vs good

−2.95 (−5.01, − 0.89)

0.005

−0.52

Fair

496

15.79 (4.64)

Good vs fair

−2.94 (−3.70, −2.18)

< 0.001

−0.58

Poor

240

19.83 (3.97)

Fair vs poor

−4.03 (−4.72, −3.35)

< 0.001

−0.93

 Month 1

Excellent

71

1.63 (2.02)

–

–

–

–

Very good

177

3.85 (2.72)

Excellent vs very good

−2.22 (−2.92, −1.52)

< 0.001

−0.93

Good

175

7.27 (4.00)

Very good vs good

−3.42 (−4.14, −2.70)

< 0.001

−1.00

Fair

101

11.40 (4.63)

Good vs fair

−4.12 (−5.17, −3.08)

< 0.001

−0.95

Poor

14

16.29 (4.05)

Fair vs poor

−4.89 (−7.47, −2.31)

< 0.001

−1.12

 Month 3

Excellent

89

1.46 (2.09)

–

–

–

–

Very good

126

3.64 (2.53)

Excellent vs very good

−2.18 (−2.83, −1.54)

< 0.001

−0.94

Good

98

7.58 (4.59)

Very good vs good

−3.94 (−4.89, −2.99)

< 0.001

−1.06

Fair

52

11.27 (4.63)

Good vs fair

−3.69 (−5.25, −2.13)

< 0.001

−0.80

Poor

7

19.57 (2.37)

Fair vs poor

−8.30 (−11.89, −4.72)

< 0.001

−2.26

 Month 6

Excellent

57

1.58 (1.93)

–

–

–

–

Very good

71

3.23 (2.13)

Excellent vs very good

−1.65 (−2.36, −0.93)

< 0.001

−0.81

Good

57

6.81 (3.99)

Very good vs good

−3.58 (−4.67, −2.49)

< 0.001

−1.12

Fair

16

12.75 (5.41)

Good vs fair

−5.94 (−8.39, −3.50)

< 0.001

−1.25

Poor

5

17.40 (3.36)

Fair vs poor

−4.65 (−10.06, 0.76)

0.088

−0.94^a

 Baseline

No effect

0

–

–

–

–

–

Small

21

13.67 (4.86)

–

–

–

–

Moderate

351

12.74 (5.26)

Small vs moderate

0.92 (−1.39, 3.24)

0.433

0.18

Very large

511

16.85 (4.66)

Moderate vs very large

−4.11 (−4.78, −3.44)

< 0.001

−0.83

Extremely large

127

20.79 (3.48)

Very large vs extremely large

−3.94 (−4.80, −3.07)

< 0.001

−0.96

 Month 1

No effect

137

2.05 (1.82)

Small

214

5.25 (3.08)

No vs small

−3.20 (−3.77, −2.63)

< 0.001

−1.26

Moderate

107

8.66 (3.75)

Small vs moderate

−3.41 (−4.18, −2.64)

< 0.001

−0.99

Very large

67

13.43 (4.39)

Moderate vs very large

−4.77 (−6.00, −3.54)

< 0.001

−1.17

Extremely large

13

16.77 (3.49)

Very large vs extremely large

−3.34 (−5.91, −0.76)

0.012

−0.84

 Month 3

No effect

136

1.75 (1.78)

–

–

–

–

Small

131

4.83 (2.83)

No vs small

−3.08 (−3.65, −2.52)

< 0.001

−1.31

Moderate

65

8.71 (3.78)

Small vs moderate

−3.88 (−4.82, −2.93)

< 0.001

−1.16

Very large

30

14.00 (4.18)

Moderate vs very large

−5.29 (−7.00, −3.58)

< 0.001

−1.33

Extremely large

10

19.80 (2.35)

Very large vs extremely large

−5.80 (−8.63, −2.97)

< 0.001

−1.64^a

 Month 6

No effect

95

1.91 (1.79)

–

–

–

–

Small

64

4.61 (3.24)

No vs small

−2.70 (−3.50, −1.91)

< 0.001

−1.03

Moderate

27

8.74 (3.39)

Small vs moderate

−4.13 (−5.63, −2.63)

< 0.001

−1.25

Very large

18

14.06 (4.52)

Moderate vs very large

−5.31 (−7.69, −2.94)

< 0.001

−1.28^a

Extremely large

2

16.50 (7.78)

Very large vs extremely large

−2.44 (−9.89, 5.01)

0.499

−0.35^a