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Table 7 Average reduction in ADCT total score by improvement in Patient Global Assessment of Disease (PGAD) and Dermatology Life Quality Index (DLQI)

From: Validation of the Atopic Dermatitis Control Tool (ADCT©) using a longitudinal survey of biologic-treated patients with atopic dermatitis

  Overall sample Uncontrolled patients (ADCT ≥7 at baseline)
N Mean reduction N Mean reduction
Reduction in ADCT total score per 1-level improvement in PGADa 1570 5.30*** (5.14, 5.46) 1479 5.43*** (5.27, 5.59)
Reduction in ADCT total score per 1-level improvement in DLQI bandsb 1574 5.20*** (5.05, 5.35) 1483 5.42*** (5.27, 5.58)
Reduction in ADCT total score per 4-point improvement in DLQI total scoreb 1574 3.90*** (3.80, 4.00) 1483 4.03*** (3.92, 4.12)
  1. ***p < 0.001; aPatients who reported excellent PGAD at baseline were excluded from this analysis due to lack of variability; bNo patients had 0 or 1 DLQI scores at baseline and therefore no patients were excluded from this analysis
  2. ADCT Atopic Dermatitis Control Tool