The ceramide [NP]/[NS] ratio in the stratum corneum is a potential marker for skin properties and epidermal differentiation

Table 1 Correlation coefficients between SC functional parameters (TEWL and capacitance) and the ratio of Cer subclasses

Correlation coefficients (r_S)
		AD and control		Pso and control
		TEWL (gm^− 2 h^− 1)	Capacitance (AU)	TEWL (gm^− 2 h^− 1)	Capacitance (AU)
Ratio	NP/NS	− 0.73***	0.56**	−0.63**	0.64***
	NH/NS	−0.78***	0.61**	−0.58**	0.73***
	NP/AS	−0.72***	0.57**	−0.63**	0.70***
	NH/AS	−0.76***	0.57**	−0.56**	0.75***
	NDS/AS	−0.63***	0.58**	−0.56**	0.70***
	AH/AS	−0.79***	0.64**	−0.62**	0.78***
	EOP/AS	−0.74***	0.62**	−0.69***	0.70***

The group of atopic dermatitis (AD) patients (n = 8) and healthy control subjects (n = 7). The group of psoriasis (Pso) patients (n = 10) and healthy control subjects (n = 9). ** and *** denote significant correlations of p < 0.01 and p < 0.001, respectively. Spearman’s correlation; the correlation coefficients (r_S) and p-values are shown. TEWL Transepidermal water loss, AU Arbitrary units

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