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Table 1 Top findings for hair follicle eQTLs

From: Mapping of cis-acting expression quantitative trait loci in human scalp hair follicles

Gene # eQTLs Best eSNP Chr Position A1 A2 P FDR Effect
Top 20 independent eQTLs (discovery sample)
IPO8 183 rs7326 12 30,782,301 G A 5.17E-31 1.56E-24 −0.6840
ATP5MD 95 rs2271751 10 105,175,131 C T 5.80E-26 3.21E-20 1.1004
C17ORF97 35 rs11150881 17 259,304 G A 2.18E-25 1.18E-19 0.6600
TIMM10 9 rs3851117 11 57,237,113 A G 4.60E-25 2.11E-19 −0.8391
KCTD10 211 rs4766601 12 109,890,080 C G 9.89E-25 4.49E-19 0.5773
C5ORF35/SETD9 50 rs2591963 5 56,237,135 A T 1.50E-24 6.43E-19 −0.6930
NDUFS5 45 rs374279960 1 39,484,742 G T 2.36E-24 1.01E-18 −0.2496
LOC339804 267 rs3213944 2 61,372,298 G C 8.36E-24 2.50E-18 0.4471
FMO1 45 rs6674596 1 171,235,088 T A 1.04E-23 3.07E-18 1.3913
PARP12 32 rs2286197 7 139,726,467 G A 1.19E-23 3.46E-18 0.3402
SH3YL1 50 rs62114506 2 242,793 C G 1.30E-23 3.78E-18 −0.5886
PEX6 57 rs3805946 6 42,955,749 C T 1.47E-23 4.11E-18 0.5651
FN3KRP 109 rs2249888 17 80,675,738 G A 1.54E-23 4.11E-18 0.3341
BCR 44 rs131703 22 23,652,201 G A 6.23E-23 1.36E-17 0.4445
PSMG1 295 rs35064900 21 40,555,492 G A 7.92E-23 1.55E-17 −0.3917
RPS26L 47 rs773114 12 56,379,060 T A 1.14E-22 2.12E-17 0.4386
GOLGB1 24 rs9968051 3 121,384,081 G C 3.20E-22 5.56E-17 −0.6104
ERP27 182 rs12312821 12 15,077,527 T A 4.48E-22 7.63E-17 −0.6385
SLC47A2 51 rs12451902 17 19,619,063 G A 1.02E-21 1.65E-16 0.6855
ABHD12 517 rs2258728 20 25,276,343 A G 1.91E-21 2.88E-16 0.2737
Top 10 eQTLs in frontal scalp (replication sample)
TDRD6 14 rs552053483 6 46,870,456 C A 5.32E-12 4.08E-06 0.4313
CXCL1 32 rs191105830 4 75,248,687 G A 3.07E-09 7.16E-04 0.4703
ZXDC 12 rs552704609 3 126,534,497 A C 4.70E-08 0.00871 0.3945
COA4 2 rs34214542 11 74,207,014 G T 7.82E-08 0.01141 0.3317
DLG2 25 rs141374880 11 83,245,973 A G 8.60E-08 0.01141 0.4126
TADA2A 3 rs74398459 17 36,095,246 G T 1.17E-07 0.01446 0.3338
C17orf67 2 rs187188078 17 55,455,184 T C 1.46E-07 0.01761 0.6551
FAM220A 16 rs188128204 7 6,373,651 A G 2.11E-07 0.02083 0.4342
ARMC6 5 rs150042710 19 18,518,809 T C 2.40E-07 0.02262 0.6410
NUP153 10 rs115808997 6 17,571,313 T C 4.54E-07 0.03605 −0.4850
Top 10 eQTLs in occipital scalp (replication sample)
TELO2 17 rs561125041 16 1,464,247 T C 8.51E-10 3.00E-04 1.2115
LPHN1 17 rs147147550 19 14,373,177 T C 9.90E-10 3.00E-04 0.6231
ENTHD2 5 rs117860115 17 78,992,225 T C 4.10E-09 0.00121 0.1629
GCSAM 2 rs139726887 3 112,327,159 T C 3.41E-08 0.00496 0.3622
CCL2 11 rs72825069 17 32,600,928 T C 6.38E-08 0.00678 1.7221
RUFY3 3 rs115702490 4 72,452,170 T C 1.24E-07 0.01296 0.4149
GGPS1 6 rs115335216 1 236,067,212 T G 2.13E-07 0.01422 0.2215
MTF1 10 rs3935450 1 37,656,324 G T 2.65E-07 0.01763 −0.2218
CXADR 4 rs55707799 21 18,849,240 C T 3.47E-07 0.02132 −0.4272
KRT37 1 rs35490951 17 40,250,939 C A 3.65E-07 0.02132 1.8106
  1. The top 20 hair follicle eQTLs obtained from human occipital scalp in the discovery sample and the top 10 hair follicle eQTLs obtained from frontal and occipital scalp in the replication sample are shown
  2. eQTLs expression quantitative trait loci, eSNP SNP with eQTL effect, Chr chromosome, A1 effect allele, A2 other allele, P p-value, FDR false discovery rate