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  1. Study protocol

    Tight controlled dose reduction of biologics in psoriasis patients with low disease activity: a randomized pragmatic non-inferiority trial

    Psoriasis is an immune-mediated chronic inflammatory skin disorder for which several targeted biologic therapies became available in the last 10 years. Data from patients with rheumatoid arthritis revealed tha...

    Selma Atalay, Juul M. P. A. van den Reek, Lieke J. van Vugt, Marisol E. Otero, Peter C. M. van de Kerkhof, Alfons A. den Broeder, Wietske Kievit and Elke M. G. J. de Jong

    BMC Dermatology 2017 17:6

    Published on: 8 May 2017

  2. Research article

    Evaluation of therapeutic potential of VB-001, a leave-on formulation, for the treatment of moderate adherent dandruff

    Dandruff is a common scalp condition characterized by excessive scaling and itch. Aberrant colonization of the scalp by commensal Malassezia spp. is a major contributor in the multifactorial etiology of dandruff....

    Anamika Bhattacharyya, Nilu Jain, Sudhanand Prasad, Shilpi Jain, Vishal Yadav, Shamik Ghosh and Shiladitya Sengupta

    BMC Dermatology 2017 17:5

    Published on: 3 May 2017

  3. Research article

    A prospective analysis of pinch grafting of chronic leg ulcers in a series of elderly patients in rural Cameroon

    Chronic leg ulcers (CLUs) pose serious public health concerns worldwide. They mainly affect the elderly population. Pinch grafting (PG) could be used to treat a variety of CLUs. However, in Cameroon, there is ...

    Benjamin Momo Kadia, Christian Akem Dimala, Desmond Aroke, Cyril Jabea Ekabe, Reine Suzanne Mengue Kadia and Alain Chichom Mefire

    BMC Dermatology 2017 17:4

    Published on: 20 March 2017

  4. Research article

    Expression profiling and bioinformatic analyses suggest new target genes and pathways for human hair follicle related microRNAs

    Human hair follicle (HF) cycling is characterised by the tight orchestration and regulation of signalling cascades. Research shows that micro(mi)RNAs are potent regulators of these pathways. However, knowledge...

    Lara M. Hochfeld, Thomas Anhalt, Céline S. Reinbold, Marisol Herrera-Rivero, Nadine Fricker, Markus M. Nöthen and Stefanie Heilmann-Heimbach

    BMC Dermatology 2017 17:3

    Published on: 22 February 2017

  5. Research article

    Skin cancer knowledge and attitudes in the region of Fez, Morocco: a cross-sectional study

    The prevalence of skin cancers is constantly increasing in Morocco, and they have gradually become more aggressive due to a significant delay in the diagnosis. Our aim was to assess the levels of awareness and...

    Awatef kelati, Hanane Baybay, Mariam Atassi, Samira Elfakir, Salim Gallouj, Mariame Meziane and Fatima Zahra Mernissi

    BMC Dermatology 2017 17:2

    Published on: 17 February 2017

  6. Research article

    Knowledge, attitudes and practices of the medical personnel regarding atopic dermatitis in Yaoundé, Cameroon

    Atopic dermatitis (AD) is a chronic, relapsing and pruritic inflammatory skin disease whose management remains unclear to most non-dermatologists. This study aimed to assess the knowledge, attitudes and practi...

    Emmanuel Armand Kouotou, Jobert Richie N. Nansseu, Alexandra Dominique Ngangue Engome, Sandra Ayuk Tatah and Anne Cécile Zoung-Kanyi Bissek

    BMC Dermatology 2017 17:1

    Published on: 16 February 2017

  7. Research article

    Treatment of plaque psoriasis with an ointment formulation of the Janus kinase inhibitor, tofacitinib: a Phase 2b randomized clinical trial

    Most psoriasis patients have mild to moderate disease, commonly treated topically. Current topical agents have limited efficacy and undesirable side effects associated with long-term use. Tofacitinib is a smal...

    Kim A. Papp, Robert Bissonnette, Melinda Gooderham, Steven R. Feldman, Lars Iversen, Jennifer Soung, Zoe Draelos, Carla Mamolo, Vivek Purohit, Cunshan Wang and William C. Ports

    BMC Dermatology 2016 16:15

    Published on: 3 October 2016

  8. Research article

    Risk factors of keloids in Syrians

    Keloid is a benign fibrous growth, which presents in scar tissue of predisposed individuals. It is a result of irregular wound healing, but the exact mechanism is unknown. However, several factors may play a r...

    Abeer Shaheen, Jamal Khaddam and Fadi Kesh

    BMC Dermatology 2016 16:13

    Published on: 20 September 2016

  9. Research article

    A multicenter, randomized, open-label pilot trial assessing the efficacy and safety of etanercept 50 mg twice weekly followed by etanercept 25 mg twice weekly, the combination of etanercept 25 mg twice weekly and acitretin, and acitretin alone in patients with moderate to severe psoriasis

    Etanercept, a soluble tumor necrosis factor receptor, and acitretin have been shown to be effective in treating psoriasis. Acitretin is widely used in Korea. However, the combination of etanercept plus acitret...

    Joo-Heung Lee, Jai-Il Youn, Tae-Yoon Kim, Jee-Ho Choi, Chul-Jong Park, Yong-Beom Choe, Hae-Jun Song, Nack-In Kim, Kwang-Joong Kim, Jeung-Hoon Lee and Hyun-Jeong Yoo

    BMC Dermatology 2016 16:11

    Published on: 25 July 2016

  10. Research article

    Patch testing in Iranian children with allergic contact dermatitis

    Allergic contact dermatitis is a common disorder in adults and children alike and appears to be on the increase. The purpose of this study was to determine the sensitization trends in Iranian children with con...

    Hossein Mortazavi, Amirhooshang Ehsani, Seyed Sajed Sajjadi, Nessa Aghazadeh and Ebrahim Arian

    BMC Dermatology 2016 16:10

    Published on: 12 July 2016

  11. Research article

    Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice

    Risk of cardiovascular disease is increased in patients with psoriasis, but molecular mechanisms linking the two conditions have not been clearly established. Lack of appropriate animal models has hampered gen...

    Marie Madsen, Peter Riis Hansen, Lars Bo Nielsen, Karsten Hartvigsen, Anders Elm Pedersen, Jan Pravsgaard Christensen, Annemarie Aarup and Tanja Xenia Pedersen

    BMC Dermatology 2016 16:9

    Published on: 11 July 2016

  12. Research article

    Enzymatic debridement for the treatment of severely burned upper extremities – early single center experiences

    Severe burns of hands and arms are complex and challenging injuries. The Standard of care (SOC) – necrosectomy with skin grafting – is often associated with poor functional or aesthetic outcome. Enzymatic debr...

    Tomke Cordts, Johannes Horter, Julian Vogelpohl, Thomas Kremer, Ulrich Kneser and Jochen-Frederick Hernekamp

    BMC Dermatology 2016 16:8

    Published on: 24 June 2016

  13. Case report

    The first Danish family reported with an AQP5 mutation presenting diffuse non-epidermolytic palmoplantar keratoderma of Bothnian type, hyperhidrosis and frequent Corynebacterium infections: a case report

    An autosomal dominant form of diffuse non-epidermolytic palmoplantar keratoderma, palmoplantar keratoderma of Bothnian type, is caused by mutations in the AQP5 gene encoding the cell-membrane water channel protei...

    Anne Bruun Krøigård, Liv Eline Hetland, Ole Clemmensen, Diana C. Blaydon, Jens Michael Hertz and Anette Bygum

    BMC Dermatology 2016 16:7

    Published on: 3 June 2016

  14. Research article

    Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo

    UV radiation induces significant DNA damage in keratinocytes and is a known risk factor for skin carcinogenesis. However, it has been reported previously that repeated and simultaneous exposure to UV and heat ...

    Leslie Calapre, Elin S. Gray, Sandrine Kurdykowski, Anthony David, Prue Hart, Pascal Descargues and Mel Ziman

    BMC Dermatology 2016 16:6

    Published on: 26 May 2016

  15. Case report

    Nipple adenoma in a female patient presenting with persistent erythema of the right nipple skin: case report, review of the literature, clinical implications, and relevancy to health care providers who evaluate and treat patients with dermatologic conditions of the breast skin

    Nipple adenoma is a very uncommon, benign proliferative process of lactiferous ducts of the nipple. Clinically, it often presents as a palpable nipple nodule, a visible nipple skin erosive lesion, and/or with ...

    Gina P. Spohn, Shannon C. Trotter, Gary Tozbikian and Stephen P. Povoski

    BMC Dermatology 2016 16:4

    Published on: 20 May 2016

  16. Case report

    Odonto-onycho-dermal dysplasia in a patient homozygous for a WNT10A nonsense mutation and mild manifestations of ectodermal dysplasia in carriers of the mutation

    Odonto-onycho-dermal dysplasia (OODD) is a rare form of ectodermal dysplasia characterized by severe oligodontia, onychodysplasia, palmoplantar hyperkeratosis, dry skin, hypotrichosis, and hyperhidrosis of the...

    Anne Bruun Krøigård, Ole Clemmensen, Hans Gjørup, Jens Michael Hertz and Anette Bygum

    BMC Dermatology 2016 16:3

    Published on: 10 March 2016

  17. Reviewer acknowledgement

    BMC Dermatology Reviewer Acknowledgement, 2015

    The editors of BMC Dermatology would like to thank all our reviewers who have contributed their time to the journal in Volume 15 (2015).

    Guangde Tu

    BMC Dermatology 2016 16:2

    Published on: 5 February 2016

  18. Research article

    Estimation of individual cumulative ultraviolet exposure using a geographically-adjusted, openly-accessible tool

    Estimates of an individual’s cumulative ultraviolet (UV) radiation exposure can be useful since ultraviolet radiation exposure increases skin cancer risk, but a comprehensive tool that is practical for use in ...

    Gefei A. Zhu, Inbar Raber, Sukolsak Sakshuwong, Shufeng Li, Angela S. Li, Caroline Tan and Anne Lynn S. Chang

    BMC Dermatology 2016 16:1

    Published on: 20 January 2016

  19. Research article

    Risk factors associated with abscess formation among patient with leg erysipelas (cellulitis) in sub-Saharan Africa: a multicenter study

    Abscess formation is a frequent local complication of leg erysipelas. In this study we aimed at identifying factors associated with abscess formation of leg erysipelas in patients in sub-Saharan African countr...

    Palokinam Vincent Pitché, Bayaki Saka, Ahy Boubacar Diatta, Ousmane Faye, Boh Fanta Diané, Abdoulaye Sangaré, Pascal Niamba, Christine Mandengue, Léon Kobengue, Assane Diop, Fatimata Ly, Mame Thierno Dieng, Alassane Dicko, Maciré Mohamed Soumah, Mohamed Cissé, Sarah Hamdan Kourouma…

    BMC Dermatology 2015 15:18

    Published on: 15 December 2015

  20. Research article

    Adherence to drug treatments and adjuvant barrier repair therapies are key factors for clinical improvement in mild to moderate acne: the ACTUO observational prospective multicenter cohort trial in 643 patients

    In acne, several studies report a poor adherence to treatments. We evaluate, in a real-life setting conditions, the impact of compliance to physician’s instructions, recommendations and adherence to the treatm...

    Raúl de Lucas, Gerardo Moreno-Arias, Montserrat Perez-López, Ángel Vera-Casaño, Sonia Aladren and Massimo Milani

    BMC Dermatology 2015 15:17

    Published on: 11 September 2015

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