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Table 3 Mean changes in lipid levels in psoriasis patients and non-psoriasis subjects from 5 years before to 5 years after psoriasis incidence/index date based on random effects models

From: Trends in lipid profiles in patients with psoriasis: a population-based analysis

Lipid measure

Five-year change before the psoriasis incidence/index date

Five-year change after the psoriasis incidence/index date

 

Psoriasis

Non-psoriasis

Psoriasis

Non-psoriasis

Total Cholesterol (TC)

−6.2 (−11.7, -0.7)*

−15.3 (−20.7, -9.9)

−15.9 (−20.3, -11.4)

−13.6 (−17.8, -9.5)

Low-density Lipoprotein

−8.3 (−13.0, -3.6)

−14.2 (−19.2, -9.2)

−13.2 (−17.1, -9.2)

−13.2 (−16.8, -9.5)

High-density Lipoprotein (HDL)

2.1 (0.8, 3.4)

1.2 (−0.1, 2.6)

1.4 (0.2, 2.5)

1.7 (0.6, 2.9)

Triglycerides

1.6 (−13.5, 16.6)

−7.0 (−18.0, 4.0)

−20.2 (−31.3, -9.0)

−15.8 (−24.5, -7.2)

TC: HDL ratio

−0.3 (−0.4, -0.1)

−0.4 (−0.6, -0.2)

−0.5 (−0.7, -0.4)

−0.5 (−0.6, -0.3)

  1. * (p=0.024) indicates difference between the trends in lipid changes between psoriasis and non-psoriasis cohorts. Values in parentheses are 95% confidence intervals.