Figure 2
From: Toll-like receptor 2 activation and comedogenesis: implications for the pathogenesis of acne
TLR activation results in IL-1α release and NF-κB activation. A) Preconfluent NHEK were treated with PGN in the presence or absence of a TLR2 neutralising antibody, and levels of IL-1α release determined by ELISA. B) Three separate cultures of preconfluent NHEK were harvested following 90 min exposure to PGN, and IκB expression relative to β-actin was determined by Western blotting.