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Table 1 Clinical criteria for IDH diagnosis

From: Human T cell lymphotropic virus type 1- associated infective dermatitis in KwaZulu Natal, South Africa

Major

Minor

1. Eczema of scalp, axillae and groin external ear and retro-auricular areas, eyelid margins, paranasal skin and/or neck

1. Positive cultures for Staphylococcus aureus and/or Beta-haemolytic streptococcus from the skin or anterior nares

2. Chronic watery nasal discharge without other signs of rhinitis and/or crusting of the anterior nares

2. Generalized fine papular rash (in most severe cases)

3. Chronic relapsing dermatitis with prompt response to appropriate therapy but prompt recurrence on withdrawal of use of antibiotic

3. Generalized lymphadenopathy with dermatopathic lymphadenitis

4. Usual onset in early childhood

4. Anaemia

5. Human T cell lymphotropic virus type 1 antibody seropositivity

5. Elevated erythrocyte sedimentation rate

 

6. Hyperimmunoglobulinaemia (IgD and IgE )

 

7. Elevated CD4 count, CD8 count, and CD4/CD8 ratio

  1. Four of the criteria required for diagnosis, with mandatory inclusion of 1,2 and 5; to meet criterion 1, at least two of the sites must be affected.