Figure 1

TOLLIP mRNA expression in six individuals with the genotype GG (ID numbers 1–6) and six individuals with the genotype CC (ID numbers 7–12) at the -526 C/G locus. Total RNA samples were extracted from EBV-transformed lymphoblastoid cell lines and mRNA levels measured by quantitative real-time PCR. For each individual, mRNA expression is shown relative to the mean expression of the six individuals with the opposite genotype. The range of expression changes is less than 2-fold for each individual except ID11. No significant differences in TOLLIP mRNA expression between genotypes were obvious.