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Fig. 2 | BMC Dermatology

Fig. 2

From: Proderm technology: a water- based lipid delivery system for dermatitis that penetrates viable epidermis and has antibacterial effects

Fig. 2

Visualization of Neosalus and its penetration into epidermis. a The foam exhibits a distribution of water and free fatty acids; which are present in anionic (hydrophilic) and neutral (hydrophobic) form. b, c Light micrographs of foam showing the structure of the foam with its liquid layers between gas (propellant) cavities. d Structures within foam are less than 1 μm (cTEM). e Normal untreated skin (H&E). f Untreated normal skin shows minimal fluorescence. g Fluorescence seen in the stratum corneum of skin treated with fluorescent-labeled petrolatum. h Fluorescence seen in the stratum corneum of skin treated with fluorescent-labeled dimethicone. i, j Skin treated with fluorescent-labeled Neosalus® shows fluorescence throughout the stratum corneum and epidermis. SC: stratum corneum, E: epidermis, D: dermis, * autofluorescence of collagen fibers

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