Parameter | Inclusion Criteria | Exclusion Criteria |
---|---|---|
P articipants | ● Studies of participants diagnosed with Paget's disease (mammary or extramammary, invasive or non-invasive) and 18 years of age or older | ● Studies of participants under 18 years of age |
I ntervention | ● Any application of a photodynamic therapy alone or in conjunction with another therapy ● All wavelengths and light sources will be considered ● Any formulation of ALA, including experimental formulations ● MAL ● All intravenous photosensitizers | ● None |
C omparator | ● All studies with or without comparators | |
O utcomes | ● Any clinical outcome, including (but not restricted to): complete lesion eradication; cosmetic results; patient satisfaction; adverse effects and the need for additional therapy | ● Studies without any defined clinical outcomes |
S tudy Design | ● Any study design including case series and case reports | ● Review articles ● Economic evaluations ● Editorials and opinion pieces |