Effectiveness of photodynamic therapy for mammary and extra-mammary Paget's disease: a state of the science review

Table 2 Characteristics of included studies

Study	Country	Diagnosis	Age range (years)	No. of patients	No. of lesions^a
Prospective case series
Li et al. (2010)[15]	China	EMPD	54-83	16	21
Raspagliesi et al. (2006)[17]	Italy	EMPD	55-75	7	11
Retrospective case reports/case series
Housel et al. (2010)[16] & Shieh et al. (2002)[11]	USA	EMPD	50-75	8	24
Thaler et al. (2010)[25]	Austria	EMPD	69	1	1
Andretta-Tanaka et al. (2009)[1]	Brazil	EMPD	67-76	4	4
Fukui et al. (2009)[44]	Japan	EMPD	66-84	5	8
Li et al. (2009)[3]	China	EMPD	75	1	1
Wang et al. (2008)[26]	China	EMPD MPD	66^b 28^b	3 1	NR^a NR^a
Liu et al. (2007)[4]	China	EMPD	64-80	5	5
T'kint & Roseeuw (2006)[45]	Belgium	EMPD	64	1	2
Kim et al. (2005)[46]	Korea	EMPD	54-73	7	NR^a
Madan et al.(2005)[21]	UK	EMPD	80	1	1
Mikasa et al. (2005)[47]	Japan	EMPD	73-92	2	NR^a
Tulchinsky et al. (2004)[8]	Israel	EMPD	49-74	2	NR^a
Zawislak et al. (2004)[18]	UK	EMPD	66	1	1
Zhu et al. (2004)[48]	China	PD^c	NR	8	8
Song et al. (2003)[49]	Korea	EMPD	51-78	2	6
Xu et al. (2002)[19]	China	EMPD MPD	50-84	8 2	8 2
Chang et al. (2001)[50]	Korea	EMPD	50-73	7	8
Runfola et al. (2000)[20]	USA	EMPD	79	1	1
Henta et al. (1999)[22]	Japan	EMPD	74	1	1
Wang et al. (1991)[23]	China	EMPD PD^c	NR NR	4 3	4 3
Kubota et al. (1986)[51]	Japan	EMPD	77	1	1
Total: 23 studies			28-92	102	136 ^a

^a total no. of lesions includes all lesions entering study; if a study did not report number of lesions it was assumed that each patient had 1 lesion
^b age only reported for 2 of 4 patients
^c unspecified Paget's disease
EMPD = extra-mammary Paget's disease, MPD = mammary Paget's disease, NR = not reported

ISSN: 1471-5945