Major | Minor |
---|---|
1. Eczema of scalp, axillae and groin external ear and retro-auricular areas, eyelid margins, paranasal skin and/or neck | 1. Positive cultures for Staphylococcus aureus and/or Beta-haemolytic streptococcus from the skin or anterior nares |
2. Chronic watery nasal discharge without other signs of rhinitis and/or crusting of the anterior nares | 2. Generalized fine papular rash (in most severe cases) |
3. Chronic relapsing dermatitis with prompt response to appropriate therapy but prompt recurrence on withdrawal of use of antibiotic | 3. Generalized lymphadenopathy with dermatopathic lymphadenitis |
4. Usual onset in early childhood | 4. Anaemia |
5. Human T cell lymphotropic virus type 1 antibody seropositivity | 5. Elevated erythrocyte sedimentation rate |
6. Hyperimmunoglobulinaemia (IgD and IgE ) | |
7. Elevated CD4 count, CD8 count, and CD4/CD8 ratio |