Single nucleotide polymorphism-based genome-wide linkage analysis in Japanese atopic dermatitis families

Enomoto, Hisako; Noguchi, Emiko; Iijima, Shigeruko; Takahashi, Takenori; Hayakawa, Kazuhito; Ito, Mikako; Kano, Toshiyuki; Aoki, Takeshi; Suzuki, Yoichi; Koga, Minori; Tamari, Mayumi; Shiohara, Tetsuo; Otsuka, Fujio; Arinami, Tadao

doi:10.1186/1471-5945-7-5

BMC Dermatology

Table 2 Results of TDT and PDT

From: Single nucleotide polymorphism-based genome-wide linkage analysis in Japanese atopic dermatitis families

rs numbers	Allele	Trans*	Not Trans**	TDT P value (corrected)	PDT P value (corrected)	Gene Name	chr	SNP position
rs717227	T	70	42	0.007818 (1)	0.009023 (1)	CHRM3	1	intron
rs1449504	C	54	21	0.0001059 (0.44)	0.002627 (1)	LRP1B	2	intron
rs1370497	A	35	60	0.009876 (1)	0.006856 (1)	FMNL2	2	intron
rs920891	A	19	36	0.02082 (1)	0.008041 (1)		3
rs1567058	T	11	30	0.002486 (1)	0.007963 (1)	ARL6	3	Intron
rs1317244	A	48	77	0.009169 (1)	0.007166 (1)	CD200	3	Intron
rs1402276	A	53	30	0.01105 (1)	0.00575 (1)	SCHIP1	3	Intron
rs889319	T	53	80	0.01881 (1)	0.009975 (1)	RAI14	5	Intron
rs40207	T	25	54	0.0009624 (0.99)	0.003361 (1)		5
rs1552104	T	76	33	0.00002976 (0.15)	0.002873 (1)		5
rs1498252	A	58	32	0.005775 (1)	0.002604 (1)		6
rs2894891	A	65	42	0.0256 (1)	0.005798 (1)		6
rs1158747	T	78	39	0.0002723 (0.78)	0.0008586 (1)	LAMA4	6	Intron
rs169902	A	33	51	0.04865 (1)	0.006104 (1)		7
rs1202169	A	74	44	0.005487 (1)	0.006487 (1)	ABCB1	7	Intron
rs1419607	A	43	75	0.003033 (1)	0.005659 (1)		7
rs901592	T	37	70	0.001298 (1)	0.003353 (1)		8
rs9071	A	36	59	0.01771 (1)	0.007423 (1)	LRRC14	8	3UTR
rs1250288	T	58	36	0.02263 (1)	0.005251 (1)		9
rs1361800	T	38	15	0.001315 (1)	0.002218 (1)	SORCS3	10	Intron
rs1034178	T	75	42	0.002129 (1)	0.006029 (1)	SORCS3	10	Intron
rs2011505	T	11	28	0.005631 (1)	0.004738 (1)	NCAM1	11	intron
rs3345	T	58	30	0.002604 (1)	0.006276 (1)	HNT	11	intron
rs2034954	A	36	68	0.001559 (1)	0.004317 (1)		12
rs954108	T	13	28	0.01778 (1)	0.006656 (1)		13
rs1462256	A	50	79	0.01034 (1)	0.009023 (1)		14
rs725463	T	65	40	0.01423 (1)	0.00625 (1)		15
rs1984372	A	58	36	0.02263 (1)	0.008914 (1)		18
rs1943919	T	37	65	0.005266 (1)	0.008719 (1)		18
rs2012035	C	30	56	0.004717 (1)	0.009644 (1)		19
rs542419	T	59	38	0.0323 (1)	0.007665 (1)		19
rs1477340	T	75	43	0.003033 (1)	0.001527 (1)	NPAS1	19	intron
rs714022	A	50	29	0.01746 (1)	0.001986 (1)	ATXN10	22	intron
rs737822	A	49	26	0.00742 (1)	0.001984 (1)		22
rs728591	A	42	70	0.007818 (1)	0.004015 (1)		22

* Number of alleles transmitted to the affected children. ** Number of alleles not transmitted to the affected children. Bonferroni correction was applied for multiple testing

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ISSN: 1471-5945

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