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Table 4 Whole genome linkage studies for ATOD

From: Single nucleotide polymorphism-based genome-wide linkage analysis in Japanese atopic dermatitis families

Year

Authors

Population

Genotyping

No. of markers

No. of families No. of ASP*

Phenotype

Linkage regions

2007

Present study

Japanese

SNPs

5861

77

ATOD

1q24

     

111

 

15q21

2004

Haagerup

Danish

Microsatellite

446

23

ATOD and specific IgE

3q26-3q24

     

N/A

 

4q15-4q14

       

18q11-18q12

2002

Bradley

Swedish

Microsatellite

367

109

ATOD

3p24-22

     

206

ATOD and specific IgE

18q21

      

ATOD and severity score

3q14

       

13a14

       

15q14

       

17q21

2001

Cookson

British

Microsatellite

385

148

ATOD

1q21

     

213

 

17q25

      

ATOD and asthma

20p

2000

Lee

European

Microsatellite

380

199

ATOD

3q21

     

N/A

  
  1. *ASP; affected sib-pairs