Fig. 1

Effect of RTA 408 on mRNA Expression of Nrf2 Target Genes in Primary Human Keratinocytes. Freshly isolated primary human keratinocytes were incubated with RTA 408 (3–1000 nM) or vehicle (DMSO, 0.1 % v/v) for 16 h and analyzed for mRNA expression of Nrf2 target genes. Data were normalized to the housekeeping gene PPIB and are presented as mean fold vehicle control ± standard error of the mean (S.E.M.). *p < 0.05 vs. vehicle control