Fig. 1

Chromosome 1 microsatellite analyses in NRAS mutated melanomas. Summary of AFLP analysis of eight chromosome 1 microsatellite markers performed in 29 NRAS Q61 mutated melanomas. Each row contains following information for one patient: identification n°, NRAS/chromosome 1 FISH result, NRAS mutant allele percentage, results of microsatellite markers LOH. NRAS gene and centromere localization are indicated. NA – non analysable, NI – non informative, NR – not realized. FISH: 1 - disomy, 2 - disomy with rares polysomic cells, 3 polysomy (A:3–4 copy, B: >4 copy), 4 - amplification, 5- monosomy, 6- high intra-tumor copy number variations of NRAS/chromosome 1