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Table 2 Known-group validity of the PGA

From: A multi-item Physician Global Assessment scale to assess psoriasis disease severity: validation based on four phase III tofacitinib studies

Category definition based on the PASI score Mean difference in PGA scores between group with PASI score = 0 and indicated PASI score group* 95% CI
Lower Higher
0 < PASI ≤ 5 −1.01 −1.04 −0.98
5 < PASI ≤ 10 −1.61 −1.65 −1.58
10 < PASI ≤ 20 −2.41 −2.44 −2.37
20 < PASI ≤ 30 −2.92 −2.96 −2.89
30 < PASI ≤ 40 −3.27 −3.31 −3.23
40 < PASI ≤ 72 −3.67 −3.73 −3.61
  1. *All p-values ≤0.0001 vs group with PASI score = 0
  2. PGA score was outcome and PASI score was categorical anchor, with no functional relationship imposed
  3. CI confidence interval, PASI Psoriasis Area and Severity Index, PGA Physician Global Assessment