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Table 6 Responsiveness of ADCT according to change in Patient Global Assessment of Disease (PGAD) and Dermatology Life Quality Index (DLQI)

From: Validation of the Atopic Dermatitis Control Tool (ADCT©) using a longitudinal survey of biologic-treated patients with atopic dermatitis

 

Correlation coefficient

Change in ADCT total score vs. change in PGAD

Spearman (95% CI)

 Month 1 vs. Baseline, n = 538

0.56*** (0.50, 0.62)

 Month 2 vs. Baseline, n = 458

0.58*** (0.51, 0.64)

 Month 3 vs. Baseline, n = 372

0.54*** (0.46, 0.61)

 Month 6 vs. Baseline, n = 206

0.60*** (0.50, 0.68)

Change in ADCT total score vs. change in DLQI bands

Spearman (95% CI)

 Month 1 vs. Baseline, n = 538

0.47*** (0.40, 0.54)

 Month 2 vs. Baseline, n = 458

0.48*** (0.41, 0.55)

 Month 3 vs. Baseline, n = 372

0.51*** (0.43, 0.58)

 Month 6 vs. Baseline, n = 206

0.50*** (0.39, 0.59)

Change in ADCT total score vs. change in DLQI total score

Pearson (95% CI)

 Month 1 vs. Baseline, n = 538

0.55*** (0.49, 0.61)

 Month 2 vs. Baseline, n = 458

0.57*** (0.50, 0.63)

 Month 3 vs. Baseline, n = 372

0.61*** (0.54, 0.67)

 Month 6 vs. Baseline, n = 206

0.60*** (0.51, 0.68)

  1. ***p < 0.001
  2. ADCT Atopic Dermatitis Control Tool, CI confidence interval