Estimated cut-off values for pemphigus severity classification according to pemphigus disease area index (PDAI), autoimmune bullous skin disorder intensity score (ABSIS), and anti-desmoglein 1 autoantibodies

Table 2 Defined categories for prediction of defined disease severity by PDAI scores in total patients according to the anti-Dsg1 values (U/ml)

Patients	Groups			Anti-Dsg1 based categorization characteristics
Patients	Moderate	Significant	Extensive	Sensitivity	Specificity	AUC
Total patients (n = 109) *	Moderate-to-significant: < 128; Significant-to-extensive: > 128			0.49	0.91	0.71
Total patients (n = 109) **	< 179	179–182.5	> 182.5	0.33	1.00	0.68
Total patients (n = 109) **	< 179	179–182.5	> 182.5	0.63	0.89	0.74

Cut-off values are calculated based on *model-based clustering analysis and **25th and 75th percentiles
Abbreviations: PDAI pemphigus disease area index, anti-Dsg1 anti-desmoglein 1, AUC area under the curve

ISSN: 1471-5945