Fig. 3

Hair follicle eQTLs overlapping genetic findings for hair-related traits. Linkage disequilibrium plots highlighting: a 31 HF eQTLs that overlapped a genomic locus shared by hair shape and hair color, b 26 HF eQTLs that overlapped a genomic locus for hair shape, with the most strongly associated SNP used as sentinel (in blue), and c one HF eQTL (blue) that overlapped a genomic locus for hair color. GWAS loci were defined through an analysis with the FUMA SNP2GENE function, applied separately to the genome-wide findings of GWAS for hair shape and hair color. The plots were generated using SNiPA. For the plot in a, rs72646785 (independent HF eQTL for the region) was used as the sentinel SNP (blue). The lead SNPs within this locus for hair shape (rs11203346) and hair color (rs72646785) are separated from each other by 2650 bp and have an LD r² = 0.99 in the 1000 Genomes Project, Phase 3 v5, European population reference panel