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Clinical dermatology

Section edited by Dr. Alexander Zink

This section considers clinical studies related to all aspects of dermatological conditions and diseases, including their treatment. This section also considers articles describing clinical trials, meta-analyses, and systematic reviews. Articles describing epidemiological studies and pathology should be directed to the relevant sections.  

  1. Melioidosis is an emerging infection in South Asia caused by Burkholderia pseudomallei with various clinical presentations that include pneumonia, bacteraemia, arthritis, and deep-seated abscesses. Various cutane...

    Authors: Sahathevan Vithoosan, Balendran Thanushah, Paramarajan Piranavan, Dayal Gamlaksha, Harindra Karunatilake and Ananda Jayanaga

    Citation: BMC Dermatology 2019 19:16

    Content type: Case report

    Published on:

  2. Increasing resistance of head lice against neurotoxic agents and safety concerns have led to the search for treatment alternatives. Dimeticones with a physical mode of action are safe, and bear a reduced risk ...

    Authors: Jorg Heukelbach, Doerte Wolf, John Marshall Clark, Hans Dautel and Kristina Roeschmann

    Citation: BMC Dermatology 2019 19:14

    Content type: Research article

    Published on:

  3. Head lice infestation (Pediculosis) is one of the most important health challenges particularly in primary school-aged children. It is often present among 6–11-year-old students in various tropical and tempera...

    Authors: Hadi Kalari, Aboozar Soltani, Kourosh Azizi, Hossein Faramarzi and Mohammad Djaefar Moemenbellah-Fard

    Citation: BMC Dermatology 2019 19:13

    Content type: Research article

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  4. Ainhum is an idiopathic dermatological disease characterized by a progressive constricting ring usually on the fifth toe, which may lead to spontaneous auto-amputation of the affected toe. Timely diagnosis and...

    Authors: Diego Nitcheu Tchouakam, Joel Noutakdie Tochie, Marc Leroy Guifo and Simeon Pierre Choukem

    Citation: BMC Dermatology 2019 19:12

    Content type: Case report

    Published on:

  5. Patch testing with a baseline series is a common tool employed when the sensitizing agent in contact dermatitis is unclear. However, for Asian countries, there are no locally validated baseline series to utili...

    Authors: B. S. D. P. Keragala, H. M. M. T. B. Herath, T. S. Keragala, M. A. M. H. Malavi, Chaturaka Rodrigo and C. N. Gunasekera

    Citation: BMC Dermatology 2019 19:10

    Content type: Research article

    Published on:

  6. Treatment options for the management of moderate to severe plaque psoriasis include phototherapy, oral systemic agents, and biologic therapy. Secukinumab, a fully human monoclonal antibody that selectively tar...

    Authors: Kim A. Papp, Melinda Gooderham, Jennifer Beecker, Charles W. Lynde, Isabelle Delorme, Ignacio Dei-Cas, Lorne Albrecht, Emmanouil Rampakakis, John S. Sampalis, Antonio Vieira, Shamiza Hussein, Olivier Chambenoit and Lenka Rihakova

    Citation: BMC Dermatology 2019 19:9

    Content type: Study protocol

    Published on:

  7. Several different Physician Global Assessment (PGA) versions have been used in clinical studies as a co-primary end point to evaluate psoriasis severity. Tofacitinib is an oral Janus kinase inhibitor. We perfo...

    Authors: Kristina Callis Duffin, Andrew G. Bushmakin, Joseph C. Cappelleri, Lotus Mallbris and Carla Mamolo

    Citation: BMC Dermatology 2019 19:8

    Content type: Research article

    Published on:

  8. We describe a case of leucocytoclasic vasculitis induced by Sofosbuvir and its disappearence after the end of the therapy. The hepatitis C virus, firstly described in 1989, is a major global health problem, wi...

    Authors: Elena Campione, Annunziata Dattola, Monia Di Prete, Daniele Di Paolo, Amedeo Ferlosio, Augusto Orlandi and Luca Bianchi

    Citation: BMC Dermatology 2019 19:6

    Content type: Case report

    Published on:

  9. Epidemiological studies to determine the pattern of skin diseases among children are important for proper health care planning and management. The purpose of this study was to describe the pattern of skin dise...

    Authors: Abraham Getachew Kelbore, Philip Owiti, Anthony J. Reid, Efa Ambaw Bogino, Lantesil Wondewosen and Blen Kassahun Dessu

    Citation: BMC Dermatology 2019 19:5

    Content type: Research article

    Published on:

  10. A defective skin barrier and bacterial colonization are two important factors in maintenance and progression of atopic dermatitis and chronic allergic/irritant hand dermatitis. A water-based lipid delivery sys...

    Authors: Alexandra Charruyer, Mats Silvander, Melinda Caputo-Janhager, Isabelle Raymond and Ruby Ghadially

    Citation: BMC Dermatology 2019 19:2

    Content type: Research article

    Published on:

  11. In Germany, work-related skin diseases are predominant within the spectrum of reported occupational diseases. Metal workers are among the high-risk professions. Offering effective prevention programs to affect...

    Authors: Annika Wilke, Günther Gediga, Andreas Goergens, Andreas Hansen, Anja Hübner, Swen Malte John, Kathrin Nordheider, Marc Rocholl, Sabine Weddeling, Britta Wulfhorst and Dorothée Nashan

    Citation: BMC Dermatology 2018 18:12

    Content type: Research article

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  12. Despite the current knowledge of UV, there is a lack of consensus among diagnostic criteria and management. In general, antihistamine therapy is regularly used for the symptomatic management of pruritus but do...

    Authors: Ivan Cherrez-Ojeda, Emanuel Vanegas, Miguel Felix, Valeria L. Mata and Annia Cherrez

    Citation: BMC Dermatology 2018 18:8

    Content type: Case report

    Published on:

  13. Acne is a chronic inflammatory condition affecting the pilosebaceous follicle that mainly affects adolescents and young adults. The aim of this study was to assess the quality of life (QOL) of patients with ac...

    Authors: Bayaki Saka, Abla Séfako Akakpo, Julienne Noude Téclessou, Abas Mouhari-Toure, Garba Mahamadou, Piham Gnossike, Waguéna Gnassingbé, Aurel Abilogoun-Chokki, Adjalamotom Tawelessi, Koussake Kombaté and Palokinam Pitché

    Citation: BMC Dermatology 2018 18:7

    Content type: Research article

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  14. Dermatophytosis management has become an important public health issue, with a large void in research in the area of disease pathophysiology and management. Current treatment recommendations appear to lose the...

    Authors: Murlidhar Rajagopalan, Arun Inamadar, Asit Mittal, Autar K. Miskeen, C. R. Srinivas, Kabir Sardana, Kiran Godse, Krina Patel, Madhu Rengasamy, Shivaprakash Rudramurthy and Sunil Dogra

    Citation: BMC Dermatology 2018 18:6

    Content type: Research article

    Published on:

  15. Biological therapies (BTs) including infliximab (IFX), adalimumab (ADL), secukinumab (SCK) and ustekinumab (UST) are approved in Japan for the treatment of psoriasis. Although the persistence rates and medical...

    Authors: Rosarin Sruamsiri, Kosuke Iwasaki, Wentao Tang and Jörg Mahlich

    Citation: BMC Dermatology 2018 18:5

    Content type: Research article

    Published on:

  16. Little is known regarding real-world health outcomes data among US psoriasis patients, but electronic health records (EHR) that collect structured data at point-of-care may provide opportunities to investigate...

    Authors: April W. Armstrong, Shonda A. Foster, Brian S. Comer, Chen-Yen Lin, William Malatestinic, Russel Burge and Orin Goldblum

    Citation: BMC Dermatology 2018 18:4

    Content type: Research article

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  17. Topical corticosteroid or corticosteroid/calcipotriol preparations are recommended first-line topical treatments of psoriasis, but a main cause for the lack of efficacy of topical treatments is considered low ...

    Authors: Mathias Tiedemann Svendsen, Flemming Andersen, Kirsten Hammond Andersen and Klaus Ejner Andersen

    Citation: BMC Dermatology 2018 18:2

    Content type: Study protocol

    Published on:

  18. Erythroderma is characterized by erythema and scaling affecting more than 90% of the body surface area. Inflammatory, neoplastic and, more rarely, infectious diseases may culminate with erythroderma. Diagnosis...

    Authors: Denis Miyashiro, Ana Paula Vieira, Maria Angela Bianconcini Trindade, João Avancini, José Antonio Sanches and Gil Benard

    Citation: BMC Dermatology 2017 17:16

    Content type: Case report

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  19. Chronic leg ulcers (CLUs) pose serious public health concerns worldwide. They mainly affect the elderly population. Pinch grafting (PG) could be used to treat a variety of CLUs. However, in Cameroon, there is ...

    Authors: Benjamin Momo Kadia, Christian Akem Dimala, Desmond Aroke, Cyril Jabea Ekabe, Reine Suzanne Mengue Kadia and Alain Chichom Mefire

    Citation: BMC Dermatology 2017 17:4

    Content type: Research article

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  20. Atopic dermatitis (AD) is a chronic, relapsing and pruritic inflammatory skin disease whose management remains unclear to most non-dermatologists. This study aimed to assess the knowledge, attitudes and practi...

    Authors: Emmanuel Armand Kouotou, Jobert Richie N. Nansseu, Alexandra Dominique Ngangue Engome, Sandra Ayuk Tatah and Anne Cécile Zoung-Kanyi Bissek

    Citation: BMC Dermatology 2017 17:1

    Content type: Research article

    Published on:

  21. Most psoriasis patients have mild to moderate disease, commonly treated topically. Current topical agents have limited efficacy and undesirable side effects associated with long-term use. Tofacitinib is a smal...

    Authors: Kim A. Papp, Robert Bissonnette, Melinda Gooderham, Steven R. Feldman, Lars Iversen, Jennifer Soung, Zoe Draelos, Carla Mamolo, Vivek Purohit, Cunshan Wang and William C. Ports

    Citation: BMC Dermatology 2016 16:15

    Content type: Research article

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  22. Sarcoidosis is a multisystemic granulomatous disease of unknown origin. Chronic cutaneous lupus erythematosus (CCLE) is an autoimmune disease that is associated with autoantibody production and T-cell dysfunct...

    Authors: Marjon Vatanchi, Kaivon Sobhani, Valerie T. Fisher and Jeffrey J. Meffert

    Citation: BMC Dermatology 2016 16:14

    Content type: Case report

    Published on:

  23. Increased prevalence of metabolic syndrome (MS) is observed in psoriasis. Metformin has shown improvement in cardiovascular risk factors while pioglitazone demonstrated anti proliferative, anti-inflammatory an...

    Authors: Surjit Singh and Anil Bhansali

    Citation: BMC Dermatology 2016 16:12

    Content type: Research article

    Published on:

  24. Etanercept, a soluble tumor necrosis factor receptor, and acitretin have been shown to be effective in treating psoriasis. Acitretin is widely used in Korea. However, the combination of etanercept plus acitret...

    Authors: Joo-Heung Lee, Jai-Il Youn, Tae-Yoon Kim, Jee-Ho Choi, Chul-Jong Park, Yong-Beom Choe, Hae-Jun Song, Nack-In Kim, Kwang-Joong Kim, Jeung-Hoon Lee and Hyun-Jeong Yoo

    Citation: BMC Dermatology 2016 16:11

    Content type: Research article

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  25. Allergic contact dermatitis is a common disorder in adults and children alike and appears to be on the increase. The purpose of this study was to determine the sensitization trends in Iranian children with con...

    Authors: Hossein Mortazavi, Amirhooshang Ehsani, Seyed Sajed Sajjadi, Nessa Aghazadeh and Ebrahim Arian

    Citation: BMC Dermatology 2016 16:10

    Content type: Research article

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  26. Skin side effects during interferon-alpha and ribavirin treatment are common, but autoimmune dermatosis triggered by interferon-alpha is rare. We describe a case of erythrodermia from exacerbated psoriasis dur...

    Authors: Eva Lemmenmeier, Barbara Gaus, Patrick Schmid and Matthias Hoffmann

    Citation: BMC Dermatology 2016 16:5

    Content type: Case report

    Published on:

  27. Nipple adenoma is a very uncommon, benign proliferative process of lactiferous ducts of the nipple. Clinically, it often presents as a palpable nipple nodule, a visible nipple skin erosive lesion, and/or with ...

    Authors: Gina P. Spohn, Shannon C. Trotter, Gary Tozbikian and Stephen P. Povoski

    Citation: BMC Dermatology 2016 16:4

    Content type: Case report

    Published on:

  28. Estimates of an individual’s cumulative ultraviolet (UV) radiation exposure can be useful since ultraviolet radiation exposure increases skin cancer risk, but a comprehensive tool that is practical for use in ...

    Authors: Gefei A. Zhu, Inbar Raber, Sukolsak Sakshuwong, Shufeng Li, Angela S. Li, Caroline Tan and Anne Lynn S. Chang

    Citation: BMC Dermatology 2016 16:1

    Content type: Research article

    Published on:

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